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Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs
Sialic acids, a group of acidic sugars abundantly expressed in the tissues of deuterostome animals but rarely found in microbes, serve as a “signature of self” for these animals. Cognate sensors for sialic acids include Siglecs, a family of transmembrane lectins of vertebrate immune systems that rec...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288428/ https://www.ncbi.nlm.nih.gov/pubmed/30564250 http://dx.doi.org/10.3389/fimmu.2018.02885 |