Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An in silico Study

Heart failure (HF) is one of the most common causes of morbidity and mortality worldwide. Although many patients suffering from HF die from sudden cardiac death caused by arrhythmias, the mechanism linking HF remodeling to an increased arrhythmogenic propensity remains incomplete. HF is typically ch...

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Detalles Bibliográficos
Autores principales: Loucks, Alexandra D., O’Hara, Thomas, Trayanova, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288429/
https://www.ncbi.nlm.nih.gov/pubmed/30564142
http://dx.doi.org/10.3389/fphys.2018.01737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288429/
https://www.ncbi.nlm.nih.gov/pubmed/30564142
http://dx.doi.org/10.3389/fphys.2018.01737

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