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Role of STIM1 in neurodegeneration

STIM1 is an endoplasmic reticulum (ER) protein with a key role in Ca(2+) mobilization. Due to its ability to act as an ER-intraluminal Ca(2+) sensor, it regulates store-operated Ca(2+) entry (SOCE), which is a Ca(2+) influx pathway involved in a wide variety of signalling pathways in eukaryotic cell...

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Detalles Bibliográficos
Autores principales: Pascual-Caro, Carlos, Espinosa-Bermejo, Noelia, Pozo-Guisado, Eulalia, Martin-Romero, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288638/
https://www.ncbi.nlm.nih.gov/pubmed/30568747
http://dx.doi.org/10.4331/wjbc.v9.i2.16