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Ca(2+) Requirements for Long-Term Depression Are Frequency Sensitive in Purkinje Cells

Cerebellar long-term depression (LTD) is a form of synaptic plasticity dependent on postsynaptic Ca(2+) changes. One fundamental question is how LTD is selectively induced by specific numbers of Ca(2+) pulses and which are the frequency and duration of this train of pulses required for LTD induction...

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Detalles Bibliográficos
Autores principales: Zamora Chimal, C. G., De Schutter, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288660/
https://www.ncbi.nlm.nih.gov/pubmed/30564097
http://dx.doi.org/10.3389/fnmol.2018.00438