Synthesis of Triazole-Substituted Quinazoline Hybrids for Anticancer Activity and a Lead Compound as the EGFR Blocker and ROS Inducer Agent

[Image: see text] A series of triazole-substituted quinazoline hybrid compounds were designed and synthesized for anticancer activity targeting epidermal growth factor receptor (EGFR) tyrosine kinase. Most of the compounds showed moderate to good antiproliferative activity against four cancer cell l...

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Detalles Bibliográficos
Autores principales: Banerji, Biswadip, Chandrasekhar, Kadaiahgari, Sreenath, Kancham, Roy, Saheli, Nag, Sayoni, Saha, Krishna Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288807/
https://www.ncbi.nlm.nih.gov/pubmed/30556027
http://dx.doi.org/10.1021/acsomega.8b01960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288807/
https://www.ncbi.nlm.nih.gov/pubmed/30556027
http://dx.doi.org/10.1021/acsomega.8b01960

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