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The Caenorhabditis elegans Oxidative Stress Response Requires the NHR-49 Transcription Factor
The overproduction of reactive oxygen species (ROS) in cells can lead to the development of diseases associated with aging. We have previously shown that C. elegans BRAP-2 (Brca1 associated binding protein 2) regulates phase II detoxification genes such as gst-4, by increasing SKN-1 activity. Previo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288832/ https://www.ncbi.nlm.nih.gov/pubmed/30297383 http://dx.doi.org/10.1534/g3.118.200727 |