Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice

We illustrate, through two case studies, that “mean-variance QTL mapping”—QTL mapping that models effects on the mean and the variance simultaneously—can discover QTL that traditional interval mapping cannot. Mean-variance QTL mapping is based on the double generalized linear model, which extends th...

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Detalles Bibliográficos
Autores principales: Corty, Robert W., Kumar, Vivek, Tarantino, Lisa M., Takahashi, Joseph S., Valdar, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288835/
https://www.ncbi.nlm.nih.gov/pubmed/30389793
http://dx.doi.org/10.1534/g3.118.200194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288835/
https://www.ncbi.nlm.nih.gov/pubmed/30389793
http://dx.doi.org/10.1534/g3.118.200194

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