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Liquid biopsy using the supernatant of a pleural effusion for EGFR genotyping in pulmonary adenocarcinoma patients: a comparison between cell-free DNA and extracellular vesicle-derived DNA

BACKGROUND: EGFR genotyping in pulmonary adenocarcinoma patients who develop pleural effusions is mostly performed using cytology or cell block slides with low sensitivity. Liquid biopsy using the supernatant of pleural effusions may be more effective because they contain many components released by...

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Detalles Bibliográficos
Autores principales: Lee, Jong Sik, Hur, Jae Young, Kim, In Ae, Kim, Hee Joung, Choi, Chang Min, Lee, Jae Chol, Kim, Wan Seop, Lee, Kye Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288853/
https://www.ncbi.nlm.nih.gov/pubmed/30526536
http://dx.doi.org/10.1186/s12885-018-5138-3