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Comparison of computational methods for the identification of topologically associating domains

BACKGROUND: Chromatin folding gives rise to structural elements among which are clusters of densely interacting DNA regions termed topologically associating domains (TADs). TADs have been characterized across multiple species, tissue types, and differentiation stages, sometimes in association with r...

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Detalles Bibliográficos
Autores principales: Zufferey, Marie, Tavernari, Daniele, Oricchio, Elisa, Ciriello, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288901/
https://www.ncbi.nlm.nih.gov/pubmed/30526631
http://dx.doi.org/10.1186/s13059-018-1596-9