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Dexmedetomidine expands monocytic myeloid-derived suppressor cells and promotes tumour metastasis after lung cancer surgery

BACKGROUND: Dexmedetomidine (DEX) has been reported to promote tumour metastases. However the underlying mechanisms remain unclear. The purpose of this study was to investigate whether DEX promotes tumour metastasis by inducing myeloid-derived suppressor cells (MDSC) in the context of surgery. METHO...

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Detalles Bibliográficos
Autores principales: Su, Xiaosan, Fan, Yaodong, Yang, Liu, Huang, Jie, Qiao, Fei, Fang, Yu, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288950/
https://www.ncbi.nlm.nih.gov/pubmed/30537999
http://dx.doi.org/10.1186/s12967-018-1727-9