p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback Loop

Understanding how p53 activates certain gene programs and not others is critical. Here, we identify low-density lipoprotein receptor-related protein 1 (LRP1), a transmembrane endocytic receptor, as a p53 target gene. We show that, although LRP1 transcript expression is upregulated in response to bot...

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Detalles Bibliográficos
Autores principales: Leslie, Patrick L., Franklin, Derek A., Liu, Yong, Zhang, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289054/
https://www.ncbi.nlm.nih.gov/pubmed/30089260
http://dx.doi.org/10.1016/j.celrep.2018.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289054/
https://www.ncbi.nlm.nih.gov/pubmed/30089260
http://dx.doi.org/10.1016/j.celrep.2018.07.010

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