Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis

Mutation accumulation during life can contribute to hematopoietic dysfunction; however, the underlying dynamics are unknown. Somatic mutations in blood progenitors can provide insight into the rate and processes underlying this accumulation, as well as the developmental lineage tree and stem cell di...

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Detalles Bibliográficos
Autores principales: Osorio, Fernando G., Rosendahl Huber, Axel, Oka, Rurika, Verheul, Mark, Patel, Sachin H., Hasaart, Karlijn, de la Fonteijne, Lisanne, Varela, Ignacio, Camargo, Fernando D., van Boxtel, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289083/
https://www.ncbi.nlm.nih.gov/pubmed/30485801
http://dx.doi.org/10.1016/j.celrep.2018.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289083/
https://www.ncbi.nlm.nih.gov/pubmed/30485801
http://dx.doi.org/10.1016/j.celrep.2018.11.014

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