Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo

BACKGROUND: It has been reported that cell inflammation pathways contribute to the development of prostaglandin E2 (PGE2)-inhibitor of DNA-binding protein-1 (ID1)-dependent radio-resistance in glioblastoma. Here, we proposed that inhibiting delta-6-desaturase (D6D) could block arachidonic acid synth...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Liang, Huaxin, Sun, Meiyan, Zhang, Lei, Xu, Huijing, Liu, Wei, Li, Yan, Zhou, Yue, Li, Yingya, Li, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289123/
https://www.ncbi.nlm.nih.gov/pubmed/30584371
http://dx.doi.org/10.2147/CMAR.S185601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289123/
https://www.ncbi.nlm.nih.gov/pubmed/30584371
http://dx.doi.org/10.2147/CMAR.S185601

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