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Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo

BACKGROUND: It has been reported that cell inflammation pathways contribute to the development of prostaglandin E2 (PGE2)-inhibitor of DNA-binding protein-1 (ID1)-dependent radio-resistance in glioblastoma. Here, we proposed that inhibiting delta-6-desaturase (D6D) could block arachidonic acid synth...

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Detalles Bibliográficos
Autores principales:	Wang, Jie, Liang, Huaxin, Sun, Meiyan, Zhang, Lei, Xu, Huijing, Liu, Wei, Li, Yan, Zhou, Yue, Li, Yingya, Li, Miao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289123/ https://www.ncbi.nlm.nih.gov/pubmed/30584371 http://dx.doi.org/10.2147/CMAR.S185601

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