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Hierarchical optimization for the efficient parametrization of ODE models

MOTIVATION: Mathematical models are nowadays important tools for analyzing dynamics of cellular processes. The unknown model parameters are usually estimated from experimental data. These data often only provide information about the relative changes between conditions, hence, the observables contai...

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Detalles Bibliográficos
Autores principales: Loos, Carolin, Krause, Sabrina, Hasenauer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289139/
https://www.ncbi.nlm.nih.gov/pubmed/30010716
http://dx.doi.org/10.1093/bioinformatics/bty514