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Hierarchical optimization for the efficient parametrization of ODE models
MOTIVATION: Mathematical models are nowadays important tools for analyzing dynamics of cellular processes. The unknown model parameters are usually estimated from experimental data. These data often only provide information about the relative changes between conditions, hence, the observables contai...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289139/ https://www.ncbi.nlm.nih.gov/pubmed/30010716 http://dx.doi.org/10.1093/bioinformatics/bty514 |