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Highly stable RGD/disulfide bridge-bearing star-shaped biodegradable nanocarriers for enhancing drug-loading efficiency, rapid cellular uptake, and on-demand cargo release
BACKGROUND: Stability, enhanced drug-loading efficiency (DLE), and specific accumulation of therapeutics at tumor sites remain major challenges for successful cancer therapy. PURPOSE: This study describes a newly developed intelligent nanosystem that integrates stealthy, active targeting, stimulus-r...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289232/ https://www.ncbi.nlm.nih.gov/pubmed/30584298 http://dx.doi.org/10.2147/IJN.S179906 |