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Sensitivity analyses for effect modifiers not observed in the target population when generalizing treatment effects from a randomized controlled trial: Assumptions, models, effect scales, data scenarios, and implementation details

BACKGROUND: Randomized controlled trials are often used to inform policy and practice for broad populations. The average treatment effect (ATE) for a target population, however, may be different from the ATE observed in a trial if there are effect modifiers whose distribution in the target populatio...

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Detalles Bibliográficos
Autores principales: Nguyen, Trang Quynh, Ackerman, Benjamin, Schmid, Ian, Cole, Stephen R., Stuart, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289424/
https://www.ncbi.nlm.nih.gov/pubmed/30533053
http://dx.doi.org/10.1371/journal.pone.0208795