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Metformin and insulin treatment prevent placental telomere attrition in boys exposed to maternal diabetes

Shortened leukocyte and placental telomeres associated with gestational diabetes mellitus (GDM) suggest this exposure triggers telomere attrition contributing to adverse outcomes. We applied high resolution Single Telomere Length Analysis (STELA) to placenta from GDM pregnancies with different treat...

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Detalles Bibliográficos
Autores principales: Garcia-Martin, Isabel, Penketh, Richard J. A., Janssen, Anna B., Jones, Rhiannon E., Grimstead, Julia, Baird, Duncan M., John, Rosalind M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289439/
https://www.ncbi.nlm.nih.gov/pubmed/30533028
http://dx.doi.org/10.1371/journal.pone.0208533