Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate capacity for non-enzymatic recombination (and...

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Detalles Bibliográficos
Autores principales: Mutschler, Hannes, Taylor, Alexander I, Porebski, Benjamin T, Lightowlers, Alice, Houlihan, Gillian, Abramov, Mikhail, Herdewijn, Piet, Holliger, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289569/
https://www.ncbi.nlm.nih.gov/pubmed/30461419
http://dx.doi.org/10.7554/eLife.43022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289569/
https://www.ncbi.nlm.nih.gov/pubmed/30461419
http://dx.doi.org/10.7554/eLife.43022

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