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Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate capacity for non-enzymatic recombination (and...
Autores principales: | Mutschler, Hannes, Taylor, Alexander I, Porebski, Benjamin T, Lightowlers, Alice, Houlihan, Gillian, Abramov, Mikhail, Herdewijn, Piet, Holliger, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289569/ https://www.ncbi.nlm.nih.gov/pubmed/30461419 http://dx.doi.org/10.7554/eLife.43022 |
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