HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo

During mammalian development, the challenge for the embryo is to override intrinsic cellular plasticity to drive cells to distinct fates. Here, we unveil novel roles for the HIPPO signaling pathway in controlling cell positioning and expression of Sox2, the first marker of pluripotency in the mouse...

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Detalles Bibliográficos
Autores principales: Frum, Tristan, Murphy, Tayler M, Ralston, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289571/
https://www.ncbi.nlm.nih.gov/pubmed/30526858
http://dx.doi.org/10.7554/eLife.42298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289571/
https://www.ncbi.nlm.nih.gov/pubmed/30526858
http://dx.doi.org/10.7554/eLife.42298

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