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HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo
During mammalian development, the challenge for the embryo is to override intrinsic cellular plasticity to drive cells to distinct fates. Here, we unveil novel roles for the HIPPO signaling pathway in controlling cell positioning and expression of Sox2, the first marker of pluripotency in the mouse...
Autores principales: | Frum, Tristan, Murphy, Tayler M, Ralston, Amy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289571/ https://www.ncbi.nlm.nih.gov/pubmed/30526858 http://dx.doi.org/10.7554/eLife.42298 |
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