Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments

Methods to systematically study subcellular RNA localization are limited and lagging behind proteomic tools. Here, we combined APEX2-mediated proximity biotinylation of proteins with photoactivatable ribonucleoside-enhanced crosslinking to simultaneously profile the proteome, as well as the transcri...

Descripción completa

Detalles Bibliográficos
Autores principales: Benhalevy, Daniel, Anastasakis, Dimitrios, Hafner, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289640/
https://www.ncbi.nlm.nih.gov/pubmed/30478324
http://dx.doi.org/10.1038/s41592-018-0220-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289640/
https://www.ncbi.nlm.nih.gov/pubmed/30478324
http://dx.doi.org/10.1038/s41592-018-0220-y

Ejemplares similares