Crystal structure of misoprostol bound to the labor inducer prostaglandin E(2) receptor

Misoprostol is a life-saving drug in many developing countries for women at risk of post-partum hemorrhaging due to its affordability, stability, ease of administration and clinical efficacy. However, misoprostol lacks receptor and tissue selectivities and thus its use is accompanied by a number of...

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Detalles Bibliográficos
Autores principales: Audet, Martin, White, Kate L., Breton, Billy, Zarzycka, Barbara, Han, Gye Won, Lu, Yan, Gati, Cornelius, Batyuk, Alexander, Popov, Petr, Velasquez, Jeffrey, Manahan, David, Hu, Hao, Weierstall, Uwe, Liu, Wei, Shui, Wenqing, Katritch, Vsevolod, Cherezov, Vadim, Hanson, Michael A., Stevens, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289721/
https://www.ncbi.nlm.nih.gov/pubmed/30510194
http://dx.doi.org/10.1038/s41589-018-0160-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289721/
https://www.ncbi.nlm.nih.gov/pubmed/30510194
http://dx.doi.org/10.1038/s41589-018-0160-y

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