Cargando…
Crystal structure of misoprostol bound to the labor inducer prostaglandin E(2) receptor
Misoprostol is a life-saving drug in many developing countries for women at risk of post-partum hemorrhaging due to its affordability, stability, ease of administration and clinical efficacy. However, misoprostol lacks receptor and tissue selectivities and thus its use is accompanied by a number of...
Autores principales: | Audet, Martin, White, Kate L., Breton, Billy, Zarzycka, Barbara, Han, Gye Won, Lu, Yan, Gati, Cornelius, Batyuk, Alexander, Popov, Petr, Velasquez, Jeffrey, Manahan, David, Hu, Hao, Weierstall, Uwe, Liu, Wei, Shui, Wenqing, Katritch, Vsevolod, Cherezov, Vadim, Hanson, Michael A., Stevens, Raymond C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289721/ https://www.ncbi.nlm.nih.gov/pubmed/30510194 http://dx.doi.org/10.1038/s41589-018-0160-y |
Ejemplares similares
-
Structural basis of the activation of a metabotropic GABA receptor
por: Shaye, Hamidreza, et al.
Publicado: (2020) -
Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase
por: Lee, Ming-Yue, et al.
Publicado: (2020) -
Foley catheter plus misoprostol versus misoprostol alone for labor induction
por: Elpo, Jhonathan Alcides, et al.
Publicado: (2023) -
Native phasing of x-ray free-electron laser data for a G protein–coupled receptor
por: Batyuk, Alexander, et al.
Publicado: (2016) -
Toward G protein-coupled receptor structure-based drug design using X-ray lasers
por: Ishchenko, Andrii, et al.
Publicado: (2019)