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Development of a NS2B/NS3 protease inhibition assay using AlphaScreen(®) beads for screening of anti-dengue activities

BACKGROUND: Dengue infection is an endemic infectious disease and it can lead to dengue fever, dengue hemorrhagic fever, and/or dengue shock syndromes. Dengue NS2B/NS3 protease complex is essential for viral replication and is a primary target for anti-dengue drug development. In this study, a NS2B/...

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Detalles Bibliográficos
Autores principales: Abduraman, Muhammad Asyraf, Hariono, Maywan, Yusof, Rohana, Rahman, Noorsaadah Abd, Wahab, Habibah A., Tan, Mei Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289942/
https://www.ncbi.nlm.nih.gov/pubmed/30560214
http://dx.doi.org/10.1016/j.heliyon.2018.e01023