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Development of a NS2B/NS3 protease inhibition assay using AlphaScreen(®) beads for screening of anti-dengue activities
BACKGROUND: Dengue infection is an endemic infectious disease and it can lead to dengue fever, dengue hemorrhagic fever, and/or dengue shock syndromes. Dengue NS2B/NS3 protease complex is essential for viral replication and is a primary target for anti-dengue drug development. In this study, a NS2B/...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289942/ https://www.ncbi.nlm.nih.gov/pubmed/30560214 http://dx.doi.org/10.1016/j.heliyon.2018.e01023 |