Microbiome-Derived Lipopolysaccharide (LPS) Selectively Inhibits Neurofilament Light Chain (NF-L) Gene Expression in Human Neuronal-Glial (HNG) Cells in Primary Culture

The remarkable co-localization of highly pro-inflammatory lipopolysaccharide (LPS) with sporadic Alzheimer’s disease (AD)-affected neuronal nuclei suggests that there may be some novel pathogenic contribution of this heat stable neurotoxin to neuronal activity and neuron-specific gene expression. In...

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Detalles Bibliográficos
Autores principales: Lukiw, Walter J., Cong, Lin, Jaber, Vivian, Zhao, Yuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289986/
https://www.ncbi.nlm.nih.gov/pubmed/30568571
http://dx.doi.org/10.3389/fnins.2018.00896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289986/
https://www.ncbi.nlm.nih.gov/pubmed/30568571
http://dx.doi.org/10.3389/fnins.2018.00896

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