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Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis

Autophagy is a regulated, intracellular degradation process that delivers unnecessary or dysfunctional cargo to the lysosome. Autophagy has been viewed as an adaptive survival response to various stresses, whereas in other cases, it promotes cell death. Therefore, both deficient and excessive autoph...

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Detalles Bibliográficos
Autores principales: Chung, Yuhyun, Lee, Juhyung, Jung, Shinae, Lee, Yangsin, Cho, Jin Won, Oh, Young J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289995/
https://www.ncbi.nlm.nih.gov/pubmed/30538224
http://dx.doi.org/10.1038/s41419-018-1229-y