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Multidrug-resistant tuberculosis (MDR-TB) strain infection in macaques results in high bacilli burdens in airways, driving broad innate/adaptive immune responses

Tuberculosis (TB) has become the most deadly infectious diseases due to epidemics of HIV/AIDS and multidrug-resistant/extensively drug-resistant TB (MDR-/XDR-TB). Although person-to-person transmission contributes to MDR-TB, it remains unknown whether infection with MDR strains resembles infection w...

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Detalles Bibliográficos
Autores principales: Yang, Enzhuo, Yang, Rui, Guo, Ming, Huang, Dan, Wang, Wandang, Zhang, Zhuoran, Chen, Crystal, Wang, Feifei, Ho, Wenzhe, Shen, Ling, Xiao, Heping, Chen, Zheng W., Shen, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290002/
https://www.ncbi.nlm.nih.gov/pubmed/30538219
http://dx.doi.org/10.1038/s41426-018-0213-z