Mechanical loading of desmosomes depends on the magnitude and orientation of external stress

Desmosomes are intercellular adhesion complexes that connect the intermediate filament cytoskeletons of neighboring cells, and are essential for the mechanical integrity of mammalian tissues. Mutations in desmosomal proteins cause severe human pathologies including epithelial blistering and heart mu...

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Detalles Bibliográficos
Autores principales: Price, Andrew J., Cost, Anna-Lena, Ungewiß, Hanna, Waschke, Jens, Dunn, Alexander R., Grashoff, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290003/
https://www.ncbi.nlm.nih.gov/pubmed/30538252
http://dx.doi.org/10.1038/s41467-018-07523-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290003/
https://www.ncbi.nlm.nih.gov/pubmed/30538252
http://dx.doi.org/10.1038/s41467-018-07523-0

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