Cargando…

GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation

Given the dense stroma and poor vascularization, access to nutrients is limited in the microenvironment of pancreatic ductal adenocarcinoma (PDA). PDA cells can efficiently recycle various metabolic substrates through the activation of different rescuing pathways, including the autophagy pathway. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Qingcai, Xu, Jin, Liang, Chen, Liu, Jiang, Hua, Jie, Zhang, Yiyin, Ni, Quanxing, Shi, Si, Yu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290009/
https://www.ncbi.nlm.nih.gov/pubmed/30538220
http://dx.doi.org/10.1038/s41419-018-1244-z