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Design Optimization of Tumor Vasculature-Bound Nanoparticles

Nanotherapy may constitute a promising approach to target tumors with anticancer drugs while minimizing systemic toxicity. Computational modeling can enable rapid evaluation of nanoparticle (NP) designs and numerical optimization. Here, an optimization study was performed using an existing tumor mod...

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Detalles Bibliográficos
Autores principales: Chamseddine, Ibrahim M., Frieboes, Hermann B., Kokkolaras, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290012/
https://www.ncbi.nlm.nih.gov/pubmed/30538267
http://dx.doi.org/10.1038/s41598-018-35675-y