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Design Optimization of Tumor Vasculature-Bound Nanoparticles
Nanotherapy may constitute a promising approach to target tumors with anticancer drugs while minimizing systemic toxicity. Computational modeling can enable rapid evaluation of nanoparticle (NP) designs and numerical optimization. Here, an optimization study was performed using an existing tumor mod...
Autores principales: | Chamseddine, Ibrahim M., Frieboes, Hermann B., Kokkolaras, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290012/ https://www.ncbi.nlm.nih.gov/pubmed/30538267 http://dx.doi.org/10.1038/s41598-018-35675-y |
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