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Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke

Although the regulation of post-ischemic inflammation is an important strategy to treat ischemic stroke, all clinical trials have failed to show its efficacy. To solve the problem, we previously developed a novel partial peptide of RANKL, microglial healing peptide 1 (MHP1), which could reduce ische...

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Detalles Bibliográficos
Autores principales: Shimamura, Munehisa, Nakagami, Hironori, Shimizu, Hideo, Mukai, Hideyuki, Watanabe, Ryosuke, Okuzono, Takeshi, Kawano, Tomohiro, Ikeda, Yuka, Hayashi, Hiroki, Yoshida, Shota, Ju, Nan, Mochizuki, Hideki, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290023/
https://www.ncbi.nlm.nih.gov/pubmed/30538259
http://dx.doi.org/10.1038/s41598-018-35898-z