CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages

Regulatory mechanisms controlling the pool size of spleen dendritic cells (DC) remain incompletely understood. DCs are continuously replenished from hematopoietic stem cells, and FLT3-mediated signals cell-intrinsically regulate homeostatic expansion of spleen DCs. Here we show that combining FLT3 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Percin, Gulce Itir, Eitler, Jiri, Kranz, Andrea, Fu, Jun, Pollard, Jeffrey W., Naumann, Ronald, Waskow, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290072/
https://www.ncbi.nlm.nih.gov/pubmed/30538245
http://dx.doi.org/10.1038/s41467-018-07685-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290072/
https://www.ncbi.nlm.nih.gov/pubmed/30538245
http://dx.doi.org/10.1038/s41467-018-07685-x

Ejemplares similares