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Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in Streptomyces piomogeues var. Hangzhouwanensis

Piericidin A1, a member of ɑ-pyridone antibiotic, exhibits various biological activities such as antimicrobial, antifungal, and antitumor properties and possesses potent respiration-inhibitory activity against insects due to its competitive binding capacity to mitochondrial complex I. The biosynthet...

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Detalles Bibliográficos
Autores principales: Li, Yan, Kong, Lingxin, Shen, Jufang, Wang, Qing, Liu, Qian, Yang, Weinan, Deng, Zixin, You, Delin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290260/
https://www.ncbi.nlm.nih.gov/pubmed/30560207
http://dx.doi.org/10.1016/j.synbio.2018.12.002