Pathogenesis of Acquired Aplastic Anemia and the Role of the Bone Marrow Microenvironment

Aplastic anemia (AA) is characterized by bone marrow (BM) hypocellularity, resulting in peripheral cytopenias. An antigen-driven and likely auto-immune dysregulated T-cell homeostasis results in hematopoietic stem cell injury, which ultimately leads to the pathogenesis of the acquired form of this d...

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Detalles Bibliográficos
Autores principales: Medinger, Michael, Drexler, Beatrice, Lengerke, Claudia, Passweg, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290278/
https://www.ncbi.nlm.nih.gov/pubmed/30568919
http://dx.doi.org/10.3389/fonc.2018.00587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290278/
https://www.ncbi.nlm.nih.gov/pubmed/30568919
http://dx.doi.org/10.3389/fonc.2018.00587

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