Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells

The integrin LFA-1 (CD11a/CD18) plays a critical role in the interaction of T cells with antigen presenting cells (APCs) to promote lymphocyte differentiation and proliferation. This integrin can be present either in a closed or in an open active conformation and its activation upon T-cell receptor...

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Detalles Bibliográficos
Autores principales: Waldt, Natalie, Seifert, Anke, Demiray, Yunus Emre, Devroe, Eric, Turk, Benjamin E., Reichardt, Peter, Mix, Charlie, Reinhold, Annegret, Freund, Christian, Müller, Andreas J., Schraven, Burkhart, Stork, Oliver, Kliche, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290345/
https://www.ncbi.nlm.nih.gov/pubmed/30568657
http://dx.doi.org/10.3389/fimmu.2018.02852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290345/
https://www.ncbi.nlm.nih.gov/pubmed/30568657
http://dx.doi.org/10.3389/fimmu.2018.02852

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