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Enhancers in the Peril lincRNA locus regulate distant but not local genes

BACKGROUND: Recently, it has become clear that some promoters function as long-range regulators of gene expression. However, direct and quantitative assessment of enhancer activity at long intergenic noncoding RNA (lincRNA) or mRNA gene bodies has not been performed. To unbiasedly assess the enhance...

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Detalles Bibliográficos
Autores principales: Groff, Abigail F., Barutcu, A. Rasim, Lewandowski, Jordan P., Rinn, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290506/
https://www.ncbi.nlm.nih.gov/pubmed/30537984
http://dx.doi.org/10.1186/s13059-018-1589-8