1,4-Disubstituted Thiosemicarbazide Derivatives are Potent Inhibitors of Toxoplasma gondii Proliferation

A series of 4-arylthiosemicarbazides substituted at the N1 position with a 5-membered heteroaryl ring was synthesized and evaluated in vitro for T. gondii inhibition proliferation and host cell cytotoxicity. At non-toxic concentrations for the host cells all studied compounds displayed excellent ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Dzitko, Katarzyna, Paneth, Agata, Plech, Tomasz, Pawełczyk, Jakub, Stączek, Paweł, Stefańska, Joanna, Paneth, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290556/
https://www.ncbi.nlm.nih.gov/pubmed/25010466
http://dx.doi.org/10.3390/molecules19079926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290556/
https://www.ncbi.nlm.nih.gov/pubmed/25010466
http://dx.doi.org/10.3390/molecules19079926

Ejemplares similares