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1,4-Disubstituted Thiosemicarbazide Derivatives are Potent Inhibitors of Toxoplasma gondii Proliferation

A series of 4-arylthiosemicarbazides substituted at the N1 position with a 5-membered heteroaryl ring was synthesized and evaluated in vitro for T. gondii inhibition proliferation and host cell cytotoxicity. At non-toxic concentrations for the host cells all studied compounds displayed excellent ant...

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Detalles Bibliográficos
Autores principales:	Dzitko, Katarzyna, Paneth, Agata, Plech, Tomasz, Pawełczyk, Jakub, Stączek, Paweł, Stefańska, Joanna, Paneth, Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290556/ https://www.ncbi.nlm.nih.gov/pubmed/25010466 http://dx.doi.org/10.3390/molecules19079926

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