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An Efficient Solvent-Free Synthesis of 2-Hydroxy-2-(trifluoromethyl)-2H-chromenes Using Silica-Immobilized L-Proline

An efficient synthesis of 2-hydroxy-2-(trifluoromethyl)-2H-chromene-3-carboxylates was carried out under solvent-free conditions in an oven or microwave oven via the Knoevenagel condensation of salicylaldehydes with ethyl trifluoroacetoacetate followed by intramolecular cyclization in the presence o...

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Detalles Bibliográficos
Autores principales: Xu, Cuilian, Yang, Guoyu, Wang, Caixia, Fan, Sufang, Xie, Lixia, Gao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290574/
https://www.ncbi.nlm.nih.gov/pubmed/24077175
http://dx.doi.org/10.3390/molecules181011964