IP(3)-Mediated Calcium Signaling Is Involved in the Mechanism of Fractalkine-Induced Hyperalgesia Response

BACKGROUND: Fractalkine is widely expressed throughout the brain and spinal cord, where it can exert effects on pain enhancement and hyperalgesia by activating microglia through CX3C chemokine receptor 1 (CX3CR1), which triggers the release of several pro-inflammatory cytokines in the spinal cord. F...

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Detalles Bibliográficos
Autores principales: Wang, Aitao, Yang, Tingting, Zhang, Lingli, Jia, Lizhou, Wu, Qingping, Yao, Shanglong, Xu, Jianjun, Yang, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290586/
https://www.ncbi.nlm.nih.gov/pubmed/30517088
http://dx.doi.org/10.12659/MSM.913787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290586/
https://www.ncbi.nlm.nih.gov/pubmed/30517088
http://dx.doi.org/10.12659/MSM.913787

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