Cargando…

Precise Dissolution Control and Bioavailability Evaluation for Insoluble Drug Berberine via a Polymeric Particle Prepared Using Supercritical CO(2)

It is still controversial whether poor aqueous solubility is the most primary reason for the low oral bioavailability of insoluble drugs. Therefore, in this study, berberine-loaded solid polymeric particles (BPs) of varied dissolution profiles with β-cyclodextrin (β-CD) as carrier were fabricated us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Jingfu, Zhang, Kerong, Zhou, Xue, Zhou, Dan, Ge, Fahuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290634/ https://www.ncbi.nlm.nih.gov/pubmed/30961123 http://dx.doi.org/10.3390/polym10111198

Ejemplares similares

Long-Term Antibacterial Film Nanocomposite Incorporated with Patchouli Essential Oil Prepared by Supercritical CO(2) Cyclic Impregnation for Wound Dressing
por: Jia, Jingfu, et al.
Publicado: (2021)

Zein/MCM-41 Nanocomposite Film Incorporated with Cinnamon Essential Oil Loaded by Modified Supercritical CO(2) Impregnation for Long-Term Antibacterial Packaging
por: Liu, Xiaojing, et al.
Publicado: (2020)

Enhancement of dissolution of atorvastatin through preparation of polymeric solid dispersions using supercritical fluid technology
por: Altaani, Bashar, et al.
Publicado: (2020)

Pure Trans-Resveratrol Nanoparticles Prepared by a Supercritical Antisolvent Process Using Alcohol and Dichloromethane Mixtures: Effect of Particle Size on Dissolution and Bioavailability in Rats
por: Ha, Eun-Sol, et al.
Publicado: (2020)

Isolation of Chalcomoracin as a Potential α-Glycosidase Inhibitor from Mulberry Leaves and Its Binding Mechanism
por: Liu, Yang, et al.
Publicado: (2022)

Preparation of Nanocrystals for Insoluble Drugs by Top-Down Nanotechnology with Improved Solubility and Bioavailability
por: Zhang, Xun, et al.
Publicado: (2020)

Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide
por: Cha, Kwang-Ho, et al.
Publicado: (2012)

Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method
por: Liu, Mengran, et al.
Publicado: (2020)

Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability
por: Cui, Hong-Xin, et al.
Publicado: (2018)

Bioavailability and hepatoprotection enhancement of berberine and its nanoparticles prepared by liquid antisolvent method
por: Sahibzada, Muhammad Umar Khayam, et al.
Publicado: (2021)

Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate
por: Sun, Ru, et al.
Publicado: (2020)

Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability
por: Han, Fei, et al.
Publicado: (2019)

Dissolution and bioavailability improvement of bioactive apigenin using solid dispersions prepared by different techniques
por: Alshehri, Sultan M., et al.
Publicado: (2019)

Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization
por: Ha, Eun-Sol, et al.
Publicado: (2015)

Itraconazole solid dispersion prepared by a supercritical fluid technique: preparation, in vitro characterization, and bioavailability in beagle dogs
por: Yin, Xuezhi, et al.
Publicado: (2015)

Impact of Insoluble Separation Layer Mechanical Properties on Disintegration and Dissolution Kinetics of Multilayer Tablets
por: Yokoyama, Reiji, et al.
Publicado: (2020)

In vitro dissolution and bioavailability study of furosemide nanosuspension prepared using design of experiment (DoE)
por: Shariare, Mohammad H., et al.
Publicado: (2019)

Itraconazole solid dispersion prepared by a supercritical fluid technique: preparation, in vitro characterization, and bioavailability in beagle dogs [Corrigendum]
Publicado: (2015)

A New Co-Crystal of Synthetic Drug Rosiglitazone with Natural Medicine Berberine: Preparation, Crystal Structures, and Dissolution
por: Guan, Xiaoshu, et al.
Publicado: (2020)

Insoluble Polymers in Solid Dispersions for Improving Bioavailability of Poorly Water-Soluble Drugs
por: Tran, Thao T.D., et al.
Publicado: (2020)

Liposomes for Enhanced Bioavailability of Water-Insoluble Drugs: In Vivo Evidence and Recent Approaches
por: Lee, Mi-Kyung
Publicado: (2020)

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process
por: Kim, Min-Soo, et al.
Publicado: (2011)

Dissolution Testing of Hardly Soluble Materials by Surface Sensitive Techniques: Clotrimazole from an Insoluble Matrix
por: Ehmann, Heike M. A., et al.
Publicado: (2014)

Editorial: Persistent endeavors for the enhancement of dissolution and oral bioavailability
por: Wu, Wei, et al.
Publicado: (2019)

Berberine nanoparticles with enhanced in vitro bioavailability: characterization and antimicrobial activity
por: Sahibzada, Muhammad Umar Khayam, et al.
Publicado: (2018)

Effect of raw material variability of glipizide on the in vitro dissolution rate and in vivo bioavailability performance: The importance of particle size
por: Zhao, Chenyao, et al.
Publicado: (2019)

Sustained-Release Solid Dispersion of High-Melting-Point and Insoluble Resveratrol Prepared through Hot Melt Extrusion to Improve Its Solubility and Bioavailability
por: Zhu, Wenjing, et al.
Publicado: (2021)

Pipeline for precise insoluble matrisome coverage in tissue extracellular matrices
por: Chen, Wei, et al.
Publicado: (2023)

Preparation and Characterization of Pickering Emulsions with Modified Okara Insoluble Dietary Fiber
por: Bao, Yue, et al.
Publicado: (2021)

Enhancement of dissolution and oral bioavailability of lacidipine via pluronic P123/F127 mixed polymeric micelles: formulation, optimization using central composite design and in vivo bioavailability study
por: Fares, Ahmed R., et al.
Publicado: (2017)

Preparation and Characterization of Water-Insoluble Gardenia Blue Pigment
por: Gao, Yakun, et al.
Publicado: (2021)

Dissolution and homogeneous photocatalysis of polymeric carbon nitride
por: Huang, Chaofeng, et al.
Publicado: (2018)

Amorphous solid dispersion preparation via coprecipitation improves the dissolution, oral bioavailability, and intestinal health enhancement properties of magnolol
por: Cao, Jia, et al.
Publicado: (2023)

Effects of Berberine and Hwangryunhaedok-Tang on Oral Bioavailability and Pharmacokinetics of Ciprofloxacin in Rats
por: Hwang, Youn-Hwan, et al.
Publicado: (2012)

Optimization of Hyaluronate-Based Liposomes to Augment the Oral Delivery and the Bioavailability of Berberine
por: Kutbi, Hussam I., et al.
Publicado: (2021)

Supersaturable organic-inorganic hybrid matrix based on well-ordered mesoporous silica to improve the bioavailability of water insoluble drugs
por: Wu, Qiaoli, et al.
Publicado: (2020)

Dissolution-Induced Nanowire Synthesis on Hot-Dip Galvanized Surface in Supercritical Carbon Dioxide
por: Kaleva, Aaretti, et al.
Publicado: (2017)

Effect of particle size on solubility, dissolution rate, and oral bioavailability: evaluation using coenzyme Q(10) as naked nanocrystals
por: Sun, Jiao, et al.
Publicado: (2012)

Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids
por: Mirza, Sabiruddin, et al.
Publicado: (2010)

Improving the Solubility, Dissolution, and Bioavailability of Metronidazole via Cocrystallization with Ethyl Gallate
por: Li, Jinhui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d2r0ldavcgh9qpd32uo180522p