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Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe

Rapid diagnosis of metastatic lymph nodes (mLNs) of colorectal cancer (CRC) is desirable either intraoperatively or in resected fresh specimens. We have developed a series of activatable fluorescence probes for peptidase activities that are specifically upregulated in various tumors. We aimed to dis...

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Detalles Bibliográficos
Autores principales: Kubo, Hidemasa, Hanaoka, Kenjiro, Kuriki, Yugo, Komatsu, Toru, Ueno, Tasuku, Kojima, Ryosuke, Kamiya, Mako, Murayama, Yasutoshi, Otsuji, Eigo, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290796/
https://www.ncbi.nlm.nih.gov/pubmed/30542087
http://dx.doi.org/10.1038/s41598-018-36062-3