Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells

INTRODUCTION: Metastasis involves the accumulation of genetic and epigenetic alterations leading to activation of prometastatic genes and inactivation of antimetastatic genes. Among epigenetic alterations, DNA hypermethylation and histone hypoacetylation are the focus of intense translational resear...

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Detalles Bibliográficos
Autores principales: Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucía, Trejo-Becerril, Catalina, Chanona-Vilchis, José, Chávez-Blanco, Alma, Domínguez-Gómez, Guadalupe, Langley, Elizabeth, García-Carrancá, Alejandro, Dueñas-González, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290866/
https://www.ncbi.nlm.nih.gov/pubmed/30584338
http://dx.doi.org/10.2147/OTT.S187306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290866/
https://www.ncbi.nlm.nih.gov/pubmed/30584338
http://dx.doi.org/10.2147/OTT.S187306

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