Mutational mechanisms of amplifications revealed by analysis of clustered rearrangements in breast cancers

BACKGROUND: Complex clusters of rearrangements are a challenge in interpretation of cancer genomes. Some clusters of rearrangements demarcate clear amplifications of driver oncogenes but others are less well understood. A detailed analysis of rearrangements within these complex clusters could reveal...

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Detalles Bibliográficos
Autores principales: Głodzik, D, Purdie, C, Rye, I H, Simpson, P T, Staaf, J, Span, P N, Russnes, H G, Nik-Zainal, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290883/
https://www.ncbi.nlm.nih.gov/pubmed/30252041
http://dx.doi.org/10.1093/annonc/mdy404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290883/
https://www.ncbi.nlm.nih.gov/pubmed/30252041
http://dx.doi.org/10.1093/annonc/mdy404

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