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BRCA1/BRCA2 Mutations Shaped by Ancient Consanguinity Practice in Southern Mediterranean Populations

The aim of this study is to investigate the involvement of consanguinity on BRCA1/2 mutation incidence in Southern Mediterranean populations and to confirm their low penetrance by comparison of their recurrence in sporadic and familial breast cancer in a context of ancient consanguinity practice. Ou...

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Detalles Bibliográficos
Autores principales: Belaiba, Fadoua, Medimegh, Imene, Bidet, Yannick, Boussetta, Sami, Baroudi, Olfa, Mezlini, Amel, Bignon, Yves Jean, El gaaied, Amel Benammar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291031/
https://www.ncbi.nlm.nih.gov/pubmed/30362333
http://dx.doi.org/10.22034/APJCP.2018.19.10.2963