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Effects of ABCC2 and SLCO1B1 Polymorphisms on Treatment Responses in Thai Metastatic Colorectal Cancer Patients Treated with Irinotecan-Based Chemotherapy

PURPOSE: Irinotecan is an anticancer medicine which is used mostly in metastatic colorectal cancer (mCRC) treatment as second or third line chemotherapy. Several factors affect its efficacy and toxicity, including pharmacogenomics. This study aimed to investigate the impacts of ABCC2 and SLCO1B1 pol...

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Detalles Bibliográficos
Autores principales: Treenert, Apatsara, Areepium, Nutthada, Tanasanvimon, Suebpong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291051/
https://www.ncbi.nlm.nih.gov/pubmed/30360603
http://dx.doi.org/10.22034/APJCP.2018.19.10.2757